Cologuard® Colonoscopy Alternative
99.94 Negative Predictive Value
If a patient received a negative test result, there was a 99.94% chance that there would be no colorectal cancer. In clinical practice, these patients would not need to undergo a screening colonoscopy.
Cologuard is intended for the qualitative detection of colorectal neoplasia-associated DNA markers and for the presence of occult hemoglobin in human stool. A positive result may indicate the presence of blood in the stool, colorectal cancer (CRC), or an adenoma (adenoma is a precancerous growth) and should be followed by a diagnostic colonoscopy. Unfortunately, 13% of patients without colorectal cancer or advanced adenomas received a positive result (false positive). Cologuard is indicated to screen adults of either sex, 45 years or older, who are at typical average-risk for CRC.
Cologuard is not for high-risk individuals, including patients with a personal history of colorectal cancer and adenomas; who have been diagnosed with a condition associated with a high risk for colorectal cancer such as IBD, chronic ulcerative colitis, Crohn’s disease; or have a family history of colorectal cancer or certain hereditary syndromes.
Positive Cologuard results should be referred for a diagnostic colonoscopy.
Helps To Rule Out Colorectal Cancer